Germania Judaica, Band III, 1350-1519, 3. Teilband : Gebietsartikel ; Einleitungsartikel und Indices

Npgrj_NN_2011 1519..1528

Expansion of the polyglutamine (polyQ) tract in human TATA-box binding protein (TBP) causes the neurodegenerative disease spinocerebellar ataxia 17 (SCA17). It remains unclear how the polyQ tract regulates normal protein function and induces selective neuropathology in SCA17. We generated transgenic mice expressing polyQ-expanded TBP. These mice showed weight loss, progressive neurological symp...

C0lc00585a 1342..1350

In this work we report on the design, microfabrication and analytical performances of a new electrochemical sensor array (ESA) which allows for the first time the simultaneous amperometric detection of nitric oxide (NO) and peroxynitrite (ONOO ), two biologically relevant molecules. The on-chip device includes individually addressable sets of gold ultramicroelectrodes (UMEs) of 50 mm diameter, ...

Op-gbev150111 1519..1532

The amino acid composition (AAC) of proteomes differs greatly between microorganisms and is associated with the environmental niche they inhabit, suggesting that these changes may be adaptive. Similarly, the oligonucleotide composition of genomes varies and mayconferadvantagesat theDNA/RNA level. These influencesoverlap inprotein-coding sequences,making itdifficult togauge their relative contri...

Themenkreis TK III: Anwendungsarchitekturen und Dienste Erstautor:

Nowadays, many projects are carried out in a collaboration of people or groups from different institutions and/or enterprises. Such a virtual organization is characterized by high communication needs but does not operate in one single environment. MetaVoIP eases the communication as it automatically combines contact information from different PBXs and provides it to all partners. For a given vi...

Wahrscheinlichkeitstheorie und Statistik vom 3 . 3 . 2009